Human PRNP/Prion Protein HEK293 Overexpression Lysate MBS8114879 from MyBioSource.com

Description

Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamental in the pathogenesis of transmissible spongiform encephalopathies. Generally, PRNP gene is associated with prion diseases, whereas variants of the PRNP gene may also explain some cases of Alzheimer disease (AD) and frontotemporal dementia (FTD) in Caucasian populations.

This Human PRNP/Prion Protein overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of PRNP/Prion Protein protein from the overexpression lysate was verified

Product Specs
ItemHuman PRNP/Prion Protein HEK293 Overexpression Lysate
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS8114879
Format1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF
ApplicationsWestern Blot (WB)
Quantity0.3 mg
Molecular Weight33kDa
NCBI Full Gene Nameprion protein
NCBI Gene AliasesGSS, PrPc, CD230, PrP27-30, p27-30, CJD, ASCR, PrP33-35C, PrP, PRIP, KURU, AltPrP
Molecule NamePRNP/Prion Protein
TypeOverexpression Lysate
Domain/Region/TerminusMet1-Gly229
Source/Expression SystemHEK293 Cells
Cell LineHEK293